Health – Peptomedica Biotech

Our services include:

Drug R&D, consulting and new process development for active pharmaceutical ingredients (APIs). Our research team, led by our two Founders, has extensive expertise in all aspects of the synthesis of pharmacologically active, highly complex organic molecules and peptides. We have recently established new R&D facilities in India and are expanding to China and Singapore. Our research has two main areas of focus in drug discovery, namely (i) the development of new anti-viral agents and (ii) the development of potent new cosmeceuticals.

Peptides : Therapeutics and Cosmeceuticals

Peptomedica Biotech founders have vast experience in working on the synthesis of therapeutic peptides and stapled peptides. The R&D activities at Peptomedica Biotech will focus on new peptide therapeutics, modified stable peptides, cosmetic peptides and making peptide drugs orally bioavailable using Co-crystal technology.

Synthesis of Cyclic Peptides of Therapeutic Value:

Self-assembling peptides for new functional materials

Supramolecular self-assembly of N-acetyl-capped beta-peptides leads to nano- to macroscale fiber formation. Del Borgo, M. P., Mechler, A. I., Traore, D. A. K., Forsyth, C. M., Wilce, J. A., Wilce, M. C. J., Aguilar, M. I., & Perlmutter, P. (2013). Angewandte Chemie – International Edition, 52(32), 8266 – 8270. Conformational stability studies of a stapled hexa-β3-peptide library. Romila D Gopalan,a,b Mark P Del Borgo,b Ylva E Bergman,a Sharon Unabia,b Roger J Mulder,c Matthew C. J. Wilce, Jacqueline A. Wilce,b Marie-Isabel Aguilarb and Patrick Perlmutter* Org. Biomol. Chem. 2012, 10, 1802-8.

Peptide vaccine development

T Cell Determinants Incorporating Amino Acid Residues Are Protease Resistant an Remain Immunogenic In Vivo.

Webb, A. I.; Dunstone, M.A.; Williamson, N. A.; Price, J.D.; de Kauwe, A.; Chen, W.; Oakley, A.; Perlmutter, P.; Aguilar, M. I.; McCluskey, J.; Rossjohn, J.; Purcell, A. W. J. Immunol., 2005, 175, 3810-3818